ZonMw grant for long-term cohort study about medically unexplained physical symptoms (MUPS)

The Department of General Practice and Elderly Care Medicine, Amsterdam Public Health research institute, VUmc, was successful in obtaining a grant of K€240 for the prolongation of the PROSPECTS study: a long-term cohort study of the course of MUPS. Principal investigator is Hans van der Wouden.
MUPS (symptoms for which no sufficient somatic explanation is found after adequate medical examination) are common in all health care settings. They are mostly self-limiting, but when they persist, they can be severe and disabling. Very little is known about the long-term course of MUPS.
The PROSPECTS observational cohort study, started by Nikki Claassen-van Dessel in 2012, recruited 325 MUPS patients in primary, secondary and tertiary care settings, aiming to assess the 3-year course of MUPS. At predefined intervals, participants repeatedly completed questionnaires about the nature, duration and severity of MUPS symptoms, health care use and various psychological and behavioural characteristics. The collected data are used to develop a prediction model for favourable and unfavourable course types.

The grant allows the research group to extend the follow-up of the PROSPECTS cohort with another 2 years, providing a unique and efficient opportunity to gain more insight into the long-term course of MUPS. Additionally, the group will evaluate three popular theoretical models for explaining the course of MUPS, which currently lack empirical underpinning. Study results will provide care givers with tools for MUPS classification and will improve patient education about the prognosis of MUPS.

For more information (in Dutch): http://prospectsstudie.nl.
Source: https://www.amsterdamresearch.org/web/public-health/news-1/tonen-op-amsterdam-public-health/zonmw-grant-for-long-term-cohort-study-about-medically-unexplained-physical-symptoms-mups-.htm